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In the pic, a woman (Witherspoon) who is planning her sister’s (Hagner) perfect wedding and the father (Ferrell) of a young bride-to-be (Viswanathan) discover that they are double -booked for their destination wedding at a remote resort on an island off the Georgia coast. When both parties decide to share the small venue, chaos ensues and disaster awaits.。丹尼斯的双亲是未受到社会支持的疯狂科学家。他们将自己的孩子监禁在孤岛的研究所，进行秘密实验，将除丹尼斯以外的一个哥哥和三个姐姐改造成了特异的人类。 某天，父母被警察拘捕、孩子们则在社工安排下到另一个小岛上居住。 问题是，除主人公以外的四名兄姐， 没有一人拥有现代人的常识……。